Project overview
This cross-sectional study examined 400 women aged 45–60 to assess the association between vasomotor symptoms (VMS)—such as hot flashes and night sweats—and cardiovascular risk in perimenopausal and postmenopausal stages. Moderate to severe VMS were significantly linked with higher systolic and diastolic blood pressure, increased LDL cholesterol and triglycerides, and elevated fasting glucose levels. These associations remained even after adjusting for age, smoking, and BMI. Notably, frequent night sweats were associated with a greater risk of metabolic syndrome. Perimenopausal women with severe VMS showed more pronounced cardiovascular changes than postmenopausal women. However, women who exercised regularly demonstrated lower risk profiles despite similar VMS severity. The findings suggest that VMS are not just quality-of-life concerns.
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