Project overview
This prospective study evaluated the effectiveness of vacuum-assisted closure (VAC) therapy compared to conventional moist saline dressing in managing diabetic foot ulcers (DFUs) of Wagner grade 2 or 3. Conducted on 52 patients at Sharda Hospital, Greater Noida, participants were randomized into two groups. Group A received VAC therapy using an indigenously assembled device, while Group B received standard saline dressings. VAC significantly outperformed conventional treatment in terms of ulcer size and depth reduction, granulation tissue formation, and shorter hospital stays. It also led to fewer secondary interventions such as amputations or grafting. Notably, the indigenous VAC system was cost-effective, reducing expenses compared to repeated saline dressings. Healing was slower in patients with poor glycemic control (HbA1C >10) and more advanced ulcers (Wagner grade 3). Overall, VAC therapy proved to be a safe, efficient, and economically viable option for DFU management, especially in resource-limited settings.
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