Project overview
This retrospective study evaluated the prognostic utility of Albumin-Bilirubin (ALBI) and Platelet-Albumin-Bilirubin (PALBI) grades, compared with the traditional Child-Pugh classification, in 74 patients undergoing hepatectomy for hepatocellular carcinoma (HCC) or hilar cholangiocarcinoma (HCCA) at a tertiary center in Kerala, India. ALBI Grade 3 was consistently linked to poorer overall survival (OS) and recurrence-free survival (RFS) in both cancer types and remained an independent predictor even in multivariate models. While Child-Pugh Class B and PALBI Grade A3 showed some prognostic association, their significance diminished after adjusting for ALBI. These findings suggest ALBI is a more objective and reliable marker of hepatic reserve than traditional methods. Its simplicity and strong prognostic accuracy support its routine use for preoperative risk stratification in hepatic malignancies. Incorporating ALBI grading could enhance surgical planning, guide patient counseling.
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