Project overview
This randomized controlled study compared the efficacy and safety of a 200 mg transdermal diclofenac patch with intravenous paracetamol (1000 mg) for postoperative pain management in 112 patients undergoing laparoscopic appendicectomy. Both groups were demographically similar, and no significant differences were observed in operative duration or complication rates. Pain scores (VAS) were comparable at 6 and 24 hours, but the control group had better analgesia at 12 hours, while the transdermal group showed superior relief at 18 hours. The need for rescue analgesia mirrored these trends. Overall, transdermal diclofenac provided sustained pain control with a favorable safety profile, positioning it as a viable alternative or adjunct to conventional analgesia in enhancing postoperative recovery and minimizing systemic side effects.
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