Project overview
This prospective observational study conducted at MOSC Medical College, Kolenchery, assessed the quality of life (QoL) in 83 children aged 4–12 years with clinically diagnosed epilepsy. Using the QOLCE-55 questionnaire, the study explored cognitive, emotional, social, and physical domains of well-being in relation to demographic factors, seizure type, treatment regimen, and clinical variables. Generalized tonic-clonic seizures were the most prevalent (66.3%), and a significant majority were on monotherapy (85.5%). Results revealed that monotherapy was associated with better cognitive, emotional, and social QoL, whereas polytherapy correlated with slightly better physical QoL. Females outperformed males in most domains, and older children showed better physical QoL. Family history and antenatal risk factors were present in a minority but highlighted potential genetic or prenatal influences. EEG abnormalities were universal among participants. Social QoL scored highest, while physical QoL was the lowest, indicating that while peer interactions were preserved, physical limitations persisted.
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