Project overview
This comparative observational study evaluated the association of vitamin D and serum calcium levels with uterine fibroids in reproductive-age women at SNMC, Agra. A total of 160 women (80 with fibroids, 80 controls) were assessed using clinical, ultrasonographic, and biochemical parameters. Results showed significantly lower mean vitamin D (18.02 ng/mL) and serum calcium levels (9.03 mg/dL) in the fibroid group compared to controls (22.19 ng/mL and 9.60 mg/dL respectively). Irregular menstrual cycles, dysmenorrhea, and fewer live births were more prevalent among fibroid patients. No significant differences were observed in BMI, smoking, or alcohol intake. Despite frequent intake of vitamin D-rich foods and sunlight exposure, deficiencies persisted in the fibroid group. The findings suggest that hypovitaminosis D and lower calcium levels may contribute to fibroid development. Screening and supplementation
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