Project overview
This prospective case-control study compares reticulocyte parameters between neonates of gestational diabetic mothers (GDM) and those born to healthy mothers. Conducted at KIMS, Bhubaneswar, from 2023–2025, the research evaluates hematologic changes due to fetal exposure to maternal hyperglycemia. Results show neonates of GDM mothers exhibit significantly elevated hemoglobin, RBC count, PCV, RDW, absolute reticulocyte count, and immature reticulocyte fraction (IRF), indicating heightened erythropoiesis, likely due to chronic intrauterine hypoxia. Despite this, reticulocyte hemoglobin (RET-He) levels remain stable, suggesting preserved hemoglobinization. Platelet and WBC indices also reveal variations, including increased neutrophils and altered platelet metrics, hinting at stress or inflammation. These hematologic shifts underline the potential for neonatal polycythemia, subclinical inflammation, and risk of iron deficiency.
This summary describes the research topic in our project library. Research findings belong to the authors; they are not outcomes of editorial support. Authors retain responsibility for their work.
Back to this project’s library page