Project overview
This retrospective study assessed the diagnostic performance of ultrasonography in detecting hypertrophic pyloric stenosis (HPS) among 160 infants presenting with non-bilious vomiting. With surgical outcomes and clinical follow-up serving as reference standards, ultrasound demonstrated a sensitivity of 88% and specificity of 80%. Pyloric muscle thickness was the most reliable sonographic parameter, with a ≥3.0 mm threshold significantly associated with true HPS cases (p=0.03). ROC curve analysis affirmed its high diagnostic utility, yielding an AUC of 0.94. While most cases correlated well between sonographic and surgical findings, diagnostic discordance—often due to pylorospasm or technical limitations—highlighted the importance of standardized imaging protocols. These findings support ultrasound as a valuable,non-invasive diagnostic modality in pediatric care and emphasize the need for operator expertise and consistent measurement techniques to optimize clinical outcomes.
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