Project overview
This cross-sectional observational study evaluated 166 adult patients with Type 2 Diabetes Mellitus (T2DM) to assess the prevalence of thyroid dysfunction (TD) and its association with diabetic complications. The study found that 24.69% of the cohort had TD, with hypothyroidism—both overt (13.25%) and subclinical (10.24%)—being the most prevalent, and hyperthyroidism observed in only 1.2% of cases. Thyroid dysfunction was notably more common in females and significantly associated with obesity (p=0.0006), poor glycemic control (HbA1c >7%; p=0.009), dyslipidemia (p=0.01), albuminuria (p=0.02), and diabetic retinopathy (p=0.01). Patients with TD also had higher HbA1c levels compared to their euthyroid counterparts, indicating worsened glycemic control. Although neuropathy and hypertension were more frequent in the TD group, their associations were not statistically significant.
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